What pH at the sites of calcification of an octocoral tells us

What pH at the sites of calcification of an octocoral tells us

Corals are marine organisms which elaborate calcium carbonate skeletons, a process known as biomineralization or calcification. More »

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Skeletal muscle is a heterogeneous, dynamic and plastic tissue, which comprises 40% of adult human body mass. More »

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Toxicants and pathogens often induce death of their target and host cells. In order to investigate the different ways they can achieve this More »

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic frameworks (MOFs) provide a versatile platform for tuning the chemical functionality of pore surfaces and thus have attracted an increasing amount of attention for applications in gas storage More »

 

3rd International Conference on Embryology and Human Genetics. Las Vegas, Nevada, USA. October 17th – 18th, 2018

It’s a great pleasure and an honor inviting you for the “3rd International Conference on Embryology and Human Genetics” to be held on October 17th – 18th, 2018 at Las Vegas, Nevada, USA. Embryology 2018 aims to

Anomalous arterial supply to the colon refuses to obey the embryonic hernia model

In 2009 and the following 2010, we have encountered the first case (Case 1) and the second case (Case 2) of anomalous arterial blood supply to the colon in our anatomical practice for the medical students. The

Turing instability: life’s unique defiance of the second law of thermodynamics

Our psychological ‘arrow of time’ is conditioned by the Second Law of Thermodynamics, i.e. by the law of increase in entropy. A drop of blue ink will spread in water, as would white milk in black coffee.

Novel structural features of cowpea cystatins explain their remarkable stability to temperature and pH

Proteinase inhibitors are proteins that regulate the fate of proteolysis in animal and plant organisms. Phytocystatins are plant inhibitors targeting cysteine proteinases from endogenous origins, like that encountered in papaya and pineapple fruits, as well as proteases

Chemically-stimulated production of receptors and ion channels in insect cells

Because primary cultures of insect cells are laborious to produce and maintain and have relatively short term cellular longevity, they are inadequate for insecticide screening, but do have utility for pharmacological experiments.  Insecticide discovery by industry typically

P2X7 antagonism: a specific tool to decrease inflammatory status in human atherosclerotic vessels?

Atherosclerosis is a dynamic progressive disease of the large arteries characterized by the tendency to accumulate lipids, inflammatory cells, smooth muscle cells and extracellular matrix within the sub-endothelial space, and progressing in unpredictable way to different stage.

Rapid identification of respiratory syncytial virus

Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract diseases in infancy and early childhood. A rapid, simple, and accurate plaque assay for RSV identification is one of the most important procedures in

Unraveling the need of vitamin E during early embryonic brain development

During early vertebrate development, the dorsal ectoderm forms the primordium of the central nervous system along the rostro-caudal axis: the neural tube. The closure of the neural tube is a complex process that depends on adequate genetic

If you need a reason to become a furry pet lover, how about their ability to help protect kids from allergies and obesity?

For decades, we have known that children growing up with furry pets have lower rates of asthma than those who do not, an observation attributed to the hygiene hypothesis. As our knowledge of the human microbiome has

Micro-Flow Imaging: spotlight on PLGA microparticle agglomeration

Since the 1980s, engineers are capable of precisely controlling fluids inside channels of a few microliter or less. Recent advances in microfluidics have led to the development of powerful analytical techniques. One of those techniques is Micro-Flow

Internal structure of scaly armor enables bite resistance in the African Pangolin

Natural materials often exhibit excellent mechanical properties that are packaged within lightweight structures. This exceptional performance of natural materials is achieved through efficient use of architectural design, which is difficult to replicate synthetically. Recent efforts in solid

Unlocking the anticoagulant potential of Barrel Jellyfish tentacle extract

Cnidarians in spite of their toxicity have long been indicated as a potential source of natural bioactive compounds of pharmacological concern useful to develop new drugs or biomedical materials. A number of metabolites, anti-cancer, anti-microbial and anti-oxidant

Obesity fuels breast carcinogenesis: What is the molecular basis?

Excess body weight is associated with the primary risk of 13 distinct cancers and is generally considered a poor prognostic indicator for patients diagnosed with a variety of malignancies. Obesity is increasingly recognized as a risk factor

The longest single crystal structure confirmed azaacene derivative: one step forward large conjugation molecules

Organic semiconductors are supposed to be the next generation semiconductors, which shows many great advantages over silicon. For example, their devices are easier and cheaper for fabricating and can be flexible. Their variable molecular structures can be

Linear-shaped and ring-shaped Re(I) multinuclear complexes work as highly photofunctional molecule

Octahedral six coordinated rhenium(I) (Re) diimine complexes with three carbonyl ligands show long-lived and strong room-temperature luminescence, attributed to a low-lying triplet metal-to-ligand charge-transfer (3MLCT) excited state. Tunability of their properties emerges from synthetic versatility and therefore

World Congress on Advanced Pharmacy and Clinical Research. Sydney, Australia. July 16-17, 2018

Conference Series LLC Ltd invites all the participants from all over the world to attend the “World Congress on Advanced Pharmacy and Clinical Research” during July 16-17, 2018 at Sydney, Australia which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

More intensive anticoagulation is associated with a lower stroke risk after elective cardioversion in atrial fibrillation

Atrial fibrillation (AF) is the most common arrhythmia of the heart and elective cardioversion (ECV) is a common procedure in converting AF to normal sinus rhythm. AF carries an increased risk for stroke and a substantial portion

What response of skin blood flow in hindlimb does electrical stimulation of forelimb induce?

The nervous system includes the central nervous system (CNS) and autonomic nervous system (ANS). Abundant evidence exists to show that structures and functions of the CNS in humans are bilaterally asymmetrical. The best known example of brain

Molecular transformation from monocyclic to chiral tricyclic scaffold by using organonickel catalyst

Waste-free (or -minimized) molecular transformations from chemical feedstocks to complex structures is a state of the art, as it provides a cost-effective, environmentally benign and practical route to natural products as well as active pharmaceutical candidates (API).

Modern medicine is poisoned by professional arrogance

Modern medicine is poisoned by professional arrogance. The antidote is professional humility. The arrogance is exacting a high price. Several examples prove the point. For forty years physicians regularly irradiated the thymus glands of children because of