Tag Archives: virus
What can computational tools tell us about one of the non-structural proteins on Zika virus?
Zika virus has come to global attention even when it only causes mild symptoms to none. Then, why WHO declared a global emergency in 2016? Beside the rapid expansion of the outbreak through Asia and Latin America,
Getting health allies from agriculture enemies
In recent years, research in nanotechnologies has demonstrated that nanometer-sized particles constructed using a wide array of materials (e.g. metals, lipids, polymers, proteins) can offer answers to unmet questions concerning drug/vaccine delivery. Ideally, these systems should prevent
Virus chainmail: protective and porous metal-organic framework grown on a virus
Biomineralization describes a process of programmable accumulation, concentration, and construction of inorganic ions regulated by organisms to form both amorphous and crystalline materials that possess well–controlled chemical components, microstructures, morphologies, and functionalities. For instance, skeletons and shells
Epstein Barr Virus (EBV) infection empowers B lymphocytes for autoimmunity
The human body is under constant threat of foreign invaders (bacteria, viruses, parasites) that can cause infectious diseases. The reason why this often does not occur is the immune system, a complex collection of molecules and cells
How realistic is the potential global spread of Zika virus and should we all be worried?
Unless you have taken a holiday on Mars for the whole of this year no doubt by now you will have heard of Zika. This is the virus that has emerged in the last 18 months to
Zika virus infection during pregnancy and small heads: What is the connection and what can be seen by imaging
Within the last year, the outbreak of Zika virus infection in Brazil became a “public health emergency of international magnitude and concern”. The global discussions about the risk of Zika virus infection for pregnant women ahead of
Is there any association between immunosuppressant therapy and cancer related to HPV in men? Can we prevent it?
We reported a rare case of penile squamous carcinoma and inguinal metastasis in a patient with ulcerative colitis under azathioprine for many years. We could identify in the histogical study the presence of 16 and 18 HPV
Varicella. A case report: With palms and sole of foot affectation
Varicella is caused by Varicella Zoster Virus (VVZ). This virus produces two different clinical manifestations of diseases: varicella and herpex zoster. It is present all over the world. In children, varicella is a mild disease, but in
Not in my neighborhood- herpes simplex virus control of microbiome locality
The players vary, but who is really controlling occupancy of the host mucosal surfaces? The host may no longer be the sole ruling factor controlling the receptor sites for attachment of microbes, and thus membership in the
Immunogenicity of Virus Like Particles (VLP) with modified envelope (Env) protein
HIV uses a special strategy to evade the immune system during the course of infection in a human, based on features of envelope protein. The HIV Env glycoprotein that forms spikes on the surface of virus particles
Do doctors understand what helps patients with hepatitis C stay on and complete their treatment?
To be cured of hepatitis C, patients must take their medications as prescribed without missing doses and complete the full course of treatment. However, almost half of patients with hepatitis C find it difficult to take their
Outcomes of Influenza infections in hematopoietic cell transplant recipients
Influenza infection causes mild disease in most cases and severe complications in very few cases. The severity of influenza infection depends mainly on the type of influenza virus and the status of the patient’s immune system. Since
Prevalence of HIV, hepatitis B and C virus infections among candidates for orthopedic trauma surgeries
Infectious diseases are diseases caused by bacteria, virus or fungus micro organism and very readily given by one person to another. These diseases especially those that are transmitted via human blood and cause disease in humans include,
Nutritional therapy may slow down cirrhosis
One in 400 citizens of western industrialized countries suffers from chronic liver disease or its end-stage, liver cirrhosis. The only definite cure for this is a liver transplant, but the scarcity of organs and required immunosuppression render
An “appealing” small virus
In 1975 in London , an australian researcher, doctor Yvonne Cossart has detected by immunological procedures a new virus in the serum of a blood donor; the name of the blood pocket was B19 so this virus
How plant virus hides from the host cellular degradation machinery
The main goal of obligatory viral parasites is to create the perfect environment for its multiplication. Therefore, the first step is to avoid degradation by the host cellular degradation. Tomato yellow leaf curl virus (TYLCV) is not
The autonomous glycosylation of Giant, but sweet, viruses
The most of proteins carry sugars on them, which significantly modify their properties such as biological activity, solubility and resistance to protein-degrading enzymes. The sugars on proteins drive several fundamental biological mechanisms, such as hormones response, immune
Making a good drug against a bad virus better
Recent advances in the treatment of chronic Hepatitis C virus (HCV) have led to a number of treatment options using only pills taken once-a-day that can lead to the elimination of the virus – a cure. Using
In silico prediction of ebolavirus RNA polymerase inhibition
A virus at work: Let us assume that you are a virus that just infected a cell (the HOST CELL) of an individual (the PATIENT). What is your vicious objective? You want to make copies of yourself
The origin of the HIV-1 epidemic
The epidemic of human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS, is one of the world’s major public health problems, with around 37 million people currently infected with this virus. The HIV-1 epidemic originated
