Tag Archives: gene
In most cancers, the majority of the changes to the DNA (termed mutations), acquired during the disease process are inconsequential in terms of driving the cancer, however a few of the changes in a small set of
While many animal models are available “ off the shelf ” through various repositories and collaborations, generation of novel animal models has allowed for more effective studies, not limited by previously derived lines/ strains. Historically, researchers have
Microsporidia are unicellular eukaryotic parasites, infecting virtually all animals including humans. They are characterized by peculiar morphological and genetic features, which are the result of their extreme adaptation to the intracellular lifestyle. Interestingly, the infection apparatus in
The process by which a single cell, the zygote, becomes a fully formed organism has been a historic scientific enigma. Now we know that the information stored in the genes of the DNA is the responsible for
Unravel the key genes potentially related to high strength of cotton fiber by comparative phenotypic and genomic analyses
The demand of high strength of cotton fibers has been increased dramatically with the advent of modern high speed spinning technology for producing yarn. Cotton fiber is a gigantic single cell which consists of almost pure cellulose.
Resveratrol is currently known as a health-beneficial natural compound that is contained in grape skins, red wine, and other natural foods. Recent studies suggest that the compound could elongate the life spans of several organisms through a
Allelic variations within genes coding for cytokines among Orang Asli in Peninsular Malaysia: New candidate genes for future disease studies
Cytokines are a set of low molecular weight proteins/glycoproteins secreted by almost all types of cells. They regulate cell growth, immune response and blood cell development in the bone marrow. Genetic variations in cytokine genes include single
DNA is a double strand molecule composed of nucleotide subunits, consisting of three components: a sugar, a phosphate group and one of four nitrogen-containing base, (Adenine, Cytosine, Guanine or Thymine). Among humans, DNA molecules are 99.9% identical.
In this work, we analyzed a massive database of brain connectivity data from the Allen Mouse Brain Connectivity Atlas, which contains data from experiments where researchers inject viral tracers into different regions of the mouse brain. The
Non-steroidal anti-inflammatory drugs (NSAIDs) are known to act by directly suppressing the activity of cyclooxygenase, the key enzyme catalyzing the biosynthesis of prostaglandin, which induces inflammation. Therefore, NSAIDs are usually used for treating pain, inflammation, and fever.
Transgenes are genes that have moved from a donor to a recipient organism via a process known as horizontal gene transfer (HGT), in the absence of sexual reproduction. The genetic modification of crop species involves the deliberate
Pseudomonas represents an abundant bacterial group that can live in the soil. In this habitat many organisms like fungi, bacteria, plants or insects live together, often intensively interacting in close communities. The composition of these communities is
Alzheimer’s disease (AD) is a progressive dementia, affecting over 20 million people worldwide, mainly adult subjects in advanced age characterized by loss of neurons and the presence of amyloid plaques in the brain. Several families have been
Atlantic bluefin tuna (Thunus thynnus), the largest of the tuna species, is migratory top predator inhabiting the North Atlantic Ocean and the Mediterranean Sea. Extremely well adapted to life in open waters, they are able to traverse
Neuropathic pain (NP) is caused by the damage of the nervous system and one of the most common types of intractable pain. It is often severe, persistent, and refractory to available therapies. Although various analgesic has been
Protein synthesis is an energetically costly cellular process, in part due to the metabolic requirements of ribosome assembly and gene-specific messenger RNA (mRNA) production. Consequently, biosynthetic flux through the protein translation pathway is tightly regulated while translational