What pH at the sites of calcification of an octocoral tells us

What pH at the sites of calcification of an octocoral tells us

Corals are marine organisms which elaborate calcium carbonate skeletons, a process known as biomineralization or calcification. More »

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Skeletal muscle is a heterogeneous, dynamic and plastic tissue, which comprises 40% of adult human body mass. More »

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Toxicants and pathogens often induce death of their target and host cells. In order to investigate the different ways they can achieve this More »

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic frameworks (MOFs) provide a versatile platform for tuning the chemical functionality of pore surfaces and thus have attracted an increasing amount of attention for applications in gas storage More »

 

Can “low calorie”-oil enhance the secretion of incretin hormones with beneficial effects on diabetic patients?

Time courses for plasma GLP-1 following ingestion of olive oil and carrot (squares), C4-dietary oil and carrot (circles) and carrot alone (crosses).

When the human body digests dietary fat (triacylglycerol), hormones from the intestine called incretins are released from the small intestine. These hormones stimulate insulin release and inhibit food intake. The mechanism for the fat-induced incretin release involves

Nanotechnology, is it something useful for future agriculture?

Nanotechnology has been applied in various fields – biomedicine, electronic devices, renewable energy   optical electronic medicine, physics, pharmaceutics. Does it have a place in agriculture? It is generally accepted that manipulation of a crop’s native microbiome represents

Can the heart get cancer? Quite rare, but yes

Can the heart get cancer

To many, the heart seems as an unusual location for cancer. In fact, most tumors that affect the heart are metastatic in origin (start in other organs and disseminate to the heart). Primary cardiac tumors (tumors that

Hearing the light: Improved frequency resolution of optical vs. electrical inner ear stimulation

Auditory signals, including human speech, are characterized by many features, one important being sound frequency, which is perceived as pitch. In normal hearing people, the cochlea in the inner ear translates different sound frequencies into neural activation

How well can serum miRNAs diagnose amyotrophic lateral sclerosis patients?

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that damages motor neurons. As the disease progresses, patients gradually loose exercise capacity. Finally, they die due to the lack of breathability. No effective therapy was found for ALS

Effect of exposure-age on chromosomal rearrangements in methyl isocyanate (MIC) gas exposed survivors

Exposure age and chromosome aberrations

Methyl isocyanate (MIC) gas disaster appeared one of the world’s worst industrial disasters by claiming a huge toll of human lives instantly and as its aftermath effect. Besides respiratory, ophthalmic and psychological disorders, stress leukogram, including anemia,

LMO1 regulates a novel oncogenic pathway druggable for neuroblastoma

LMO1 regulates a novel oncogenic pathway druggable for neuroblastoma

Neuroblastoma (NB) is derived from neural crest cells and its main developing sites are adrenal gland and sympathetic ganglions. It is the most common extracranial solid tumor in childhood, accounting for more than 7% of malignancies in

Concerns over dosing oral anticoagulants in clinical practice

over dosing oral anticoagulants in clinical practice

Atrial fibrillation (AF) is a heart condition characterized by an abnormal rhythm leading to irregular beat. An important consequence of AF is an incomplete emptying of the atria (upper heart chamber) leading to blood stasis and, potentially,

IL-2/IL-3 interplay mediates growth of CD25(+) acute myeloid leukemia cells

acute myeloid leukemia cells

A variety of cytokines regulate the survival, growth, differentiation and apoptosis of leukemia cells. Accordingly, aberrant or excessive expression of their receptors may be associated with the biological activity of leukemia cells, and hence with the outcome

Detecting math ability with brain potentials

Detecting math ability with brain potentials

It is known that the various individuals differ in their ability to perform arithmetic calculations. Some people can find mathematics an extremely easy exercise while for others it can become an insurmountable problem. For example, a significant

International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems. Osaka, Japan. September 09-10, 2019

Cientific Group is overpowered to declare its absolute first “International Conference and Exhibition on Pharmaceutics and Novel Drug Delivery Systems”. Pharma Conferences hung on September 09-10, 2019 at Osaka, Japan. Pharmaceutica – 2019 gives a general stage

Our biological clock controls mitochondrial activity in a tissue-dependent manner

The molecular circadian clock and tissue-specific clocks

Mitochondria are the cell organelles that are responsible for the largest part of cellular energy production. Within these organelles both the tricarboxylic acid cycle (TCA cycle) and oxidative phosphorylation (OXPHOS) are taking place. In these cycles ATP,

Coastal wetland plant responses to elevated carbon dioxide

saltmarsh, coastal wetlands, nitrogen uptake, carbon dioxide

Coastal wetlands are some of the most efficient habitats globally when it comes to assimilating carbon dioxide from the atmosphere and storing it in soil. This is mainly due to the fact that many coastal wetland plant

The immunomodulatory enzyme IDO: Expression in the uterus of mares?

Detection of IDO protein in the equine endometrium by immunohistochemistry

IDO modulates immune responses. The enzyme indoleamine 2,3-dioxygenase 1 (IDO) degrades tryptophan. This amino acid is required for immune defences against pathogens, but also stimulates pathogen growth. Its degradation inhibits effector lymphocytes and retards pathogen proliferation. Thus,

Fine needle aspiration cytology for neck masses in childhood. An important tool in pediatrics

Mucin-secreting vacuolated cells, intermediate cells, and squamous cells

Neck masses can be incidental or the reason for significant concern for parents and physicians. The technique of fine-needle aspiration (FNA) cytology (FNAC) may be crucial in such settings. In 1981, the first FNA biopsy performed in

Cellular stress and AMPK activators including metformin and the anesthetic drug propofol promote restoration of human consciousness

Cellular stress and AMPK activators including Metformin

The neural mechanisms that give rise to human consciousness have been described as one of the greatest and most profound mysteries in all of modern medicine. The use of general anesthetics to induce loss of consciousness (LOC)

Keeping a clean house to suppress HER2+ breast tumor growth

Keeping a clean house to suppress HER2+ breast tumor growth

Autophagy (self-eating) is a process used by normal cells to keep a “clean house”. It degrades abnormal or damaged proteins and organelles, helps to fight infections and also provides energy during periods of fasting or exercise. Besides

The nature of bel-1 attC stabilizes its genetic environment and contributes to antibiotic resistance spreading

Schematic representation of integrons containing the blaBEL-1 gene

The rapid emergence of antibiotic resistance is a worldwide crisis, endangering the efficacy of antibiotic treatment. Multidrug resistance in Gram negatives is now recognized as an issue of worldwide interest. Those bacteria possess various resistance mechanisms compromising

Fiber refractometry revisited

Response of three sensors across three different RI Zones.

The refractive index (RI) n of a substance is generally defined as the ratio of the speed of an electromagnetic wave in vacuum c to its velocity in that substance v, or n = c/v. Refractive index

Magnetic NPs for automatic speciation analysis of inorganic arsenic in environmental water samples

Magnetic NPs for automatic speciation analysis

Arsenic is a ubiquitous element in the environment originated from natural sources as well as human activities. This element has been identified as a public health problem because it has serious toxic effects even at low exposure