Signaling crosstalk in the Ve-resistance locus of tomato
Verticillium is a fungal pathogen that causes vascular wilt disease in over 200 species of plants, including many crops. The fungus invades through the root and enters the water conducting xylem where it proliferates and rapidly becomes
International Conference on Pharmaceutical Sciences and Drug delivery. Milan, Italy. November 18-19, 2019
Theme: Optimizing Research reforms of the Pharmaceutical Industry. We cordially invite each and every interested and enthusiastic participant from all over the world to take part in the International Conference on Pharmaceutical Sciences and Drug delivery, at
Uncertain pathogenicity of mutations in Wilson gene
Wilson’s disease is caused by an autosomal recessive disorder of the hepatic copper transport of ATP 7B. The responsible gene is located on the long arm of chromosome 13. Currently more than 500 mutations are known which
Constructing a Google-Earth-like functional brain atlas
Brain, the final frontier. These are the voyages of the brain cartographers. Their continuing mission: To explore strange new maps, to seek out new areas and new functions, to BOLD-ly go where no one has gone before.
Chronic pancreatitis: an inflammatory disease of pancreas
Pancreas is very important organ in our body and it is located in the abdomen behind the stomach. Pancreas is a gland and secrets some chemicals called enzymes. It is a leaf like structure and divided in
Tobacco use in women of reproductive age
Despite reductions in rates of cigarette smoking among U.S. adults over the last 50 years, rates of smoking among women have decreased at a lesser rate compared to men. In fact, among socioeconomically disadvantaged women, rates of
Transventricular transvelar approach to trochlear nerve schwannoma
The schwannoma of the trochlear nerve is rare and originates mostly from the distal parts in the interpeduncular cistern. A lesion on the proximal segment in the inferior pineal region is extremely rare. Because of the rarity
Use of plant growth–promoting rhizobacteria (PGPR) in stressed agriculture management
Enhanced incidence of abiotic stresses influencing adversely plant growth and productivity in major crops, and thus global food security, is being witnessed all over the world. These abiotic stress factors include drought (water deficit) and flooding, salinity,
Enrichment, quantification and glycan analysis of prostate cancer oncomarker in a single step
In recent decades, there is an increasing trend in prostate cancer occurrence and mortality worldwide, caused partly by a more available diagnostics, prolonged life period but also increased risk factors present in the environment. Most commonly, age
New way to control parasites in grazing animals
Gastrointestinal nematodes are parasitic worms that pose a major threat to the health and productivity of grass-eating animals such as horses, sheep, cattle and goats. They live in the animals’ digestive system and suck their blood. Young
VMAT2: a novel biomarker for myopia
Myopia, with increasing prevalence and earlier age-of-onset, is the most common eye disease in the world. But its etiology is still unclear. Lots of studies have confirmed the hypothesis that dopamine (DA) is one of the important
Can glucose or fructose consumption impair memory?
The intake of simple sugars in the human diet has risen in the last decades, especially due to the elevated consumption of sugar-sweetened beverages. This increase in simple sugar consumption has been associated with metabolic pathologies, such
Diagnostics of seronegative rheumatoid arthritis using glycomic tools and machine learning
Rheumatoid arthritis (RA) is an inflammatory disease characterized by synovium swelling and destruction. There are two different types of rheumatoid arthritis, sometimes even believed to be two distinct disorders, namely seropositive (S+) and seronegative (S-) rheumatoid arthritis.
Targeting microRNAs for thyroid cancer therapy
The thyroid gland is a small butterfly-shaped endocrine organ located at the base of the throat, just below the Adam´s apple. Its function is to concentrate dietary iodine from the bloodstream and produce thyroid hormones, which have
An epigenetic treatment strategy puts a brake on alcohol dependence
Alcohol use disorder, commonly known as alcoholism, is a chronic debilitating psychiatric disease that affects >16 million people in the United States. Disease progression of alcoholism cycles through several different stages, characterized by preoccupation or needing to
Cost-effectiveness of rapid diagnosis of drug-resistant tuberculosis
Globally, tuberculosis (TB) is a leading cause of premature death. There are treatments for tuberculosis, but drug-resistant strains of tuberculosis have emerged, mostly due to improper or incomplete treatment. If diagnosed properly in a timely manner, extremely
Nodding syndrome, a form of river epilepsy
Nodding syndrome (NS) is a devastating epileptic condition appearing in previously healthy children between 3 and 18 years old. It is characterized by brief episodes of sudden forward dropping of the head (nodding), often accompanied by declining
Novel biosensors for the rapid detection of toxicants in foods
The specific objective of this monograph is mainly to exploit progress in nanosciences to deploy nanotechnology in affordable, mass-produced sensors, and to integrate these into components and systems (including portable ones) for mass market applications in environmental
A novel electrochemical sensor based on molecularly imprinted polymer modified MOF derived exfoliated porous carbon
In this work, we report a novel hybrid electrochemical sensor coupling exfoliated porous carbon (EPC) with molecularly imprinted polymer (MIP) for detection of lidocaine (LID). LID is a local anesthetic and antiarrhythmic drug. It is also the
The use of dry powder mannitol in respiratory disease
Asthma is an inflammatory disease of the airways causing them to be hyperresponsive to a wide range of stimuli. It is a common disease both in children and adults and most asthmatics suffer from allergies and from
