What pH at the sites of calcification of an octocoral tells us

What pH at the sites of calcification of an octocoral tells us

Corals are marine organisms which elaborate calcium carbonate skeletons, a process known as biomineralization or calcification. More »

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Skeletal muscle is a heterogeneous, dynamic and plastic tissue, which comprises 40% of adult human body mass. More »

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Toxicants and pathogens often induce death of their target and host cells. In order to investigate the different ways they can achieve this More »

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic frameworks (MOFs) provide a versatile platform for tuning the chemical functionality of pore surfaces and thus have attracted an increasing amount of attention for applications in gas storage More »

 

Crowd surfing of graphene on a lipid monolayer

In the recent years a growing interest in graphene applications lead to the development of new biosensor devices. Graphene is a powerful sensor due to its extraordinary electron mobility, unique mechanical strength and optical properties.  Consequently, the

A novel mechanism by which viral integration drives cancer

Human papillomaviruses (HPV) are a group of about 200 DNA viruses that infect the skin, or the mucous membranes of the anus, genitals and oropharyngeal cavity. HPV infections are the most common sexually transmitted disease in the

What’s really in human milk? Studying microbiota in a novel body site

Breastfeeding is the gold standard of infant nutrition as it reduces children’s risk of developing obesity, asthma, allergies, diabetes, and numerous other medical conditions. This has been historically understood by the fact that breastmilk is rich in

Diving into cell membranes with advanced solid-state NMR methods: harnessing the power of protons

Membrane proteins act as the gateways of the cell. They are essential for the signalling between cells and for the uptake of nutrients; they constitute major drug-targets in human, and their malfunctions are related to severe diseases

DNA explosions in the evolution of Hawaiian flies: consequences and questions

The chromosome set of each species carries the organism’s DNA sequences or genome. Genomes of higher organisms contain the essential coding DNA, plus the typically more abundant noncoding DNA. This segment carries various repeated DNA sequences. The

Regulation of ER Ca2+ homeostasis by disulfide reductase

Intracellular calcium is one of the most important second messengers for the regulation of various cellular processes including protein secretion, muscle contraction, gene transcription, protein degradation and apoptosis. The endoplasmic reticulum (ER) is not only the organelle

The enigma of blood pressure variation

The circulation of blood throughout the body comes from the continuous rhythmic pumping action of the heart. Specifically, a pulsatile flow of blood happens when the blood within the heart is ejected out the left ventricle into

The capillary web gets lost in diseased kidneys

Main functions of the kidney are regulating ions, pH, fluid balance and blood pressure and disposing of metabolic waste products. These functions are dependent on properly working renal blood vessels, including the smallest ones, the so called

Puberty changes how adolescents remember peer faces

Together with voices, faces are the most important source of social information for humans, even prior to birth. What is equally important to know is how the kinds of information we pay most attention to in faces

Time is Brain. Rupture of a brain aneurysm and the patients journey to the neurosurgical center

In brain infarction or traumatic injuries of the brain an immediate admission to a neurosurgical / neurological center can be life saving. With brain hemorrhages caused by a ruptured aneurysm the situation is not as clear. First

Mechanisms of diuretic plants: an overview

Ongoing research suggests several molecular mechanisms that were correlated with acute or prolonged diuretic activity of different natural products. So, it is not surprising that research on this subject is at the forefront of research on the

New strategy for the degradation of persistent pollutants in water

An hybrid solid system for the degradation of persistent pollutants was realized by mixing titanium dioxide, silica and an enzyme extracted from soybean hulls. Removal of organic pollutants from urban and industrial wastewaters is one of the

A covert authentication and security solution for GMOs

Significantly increasing worldwide utilization of genetically modified organisms (GMOs) presents challenges to ensure security, authenticity and validation of material goods and legal agreements. Similarly to the evolution witnessed in Internet protocols, strategic focus is required to anticipate,

Evolution of aquatic mammals and birds: the present predicts the past

The movement of vertebrates from the water to the land has been considered one of the great evolutionary transformations in history. However of equal evolutionary importance was the re-invasion of the aquatic environment by various groups of

The worldwide prevalence and phenotypic features of polycystic ovary syndrome

PCOS is the most common endocrine disorder among women of reproductive age. Although many studies have investigated the prevalence of PCOS, there are discrepancies in their results. Even using the same subset of diagnostic criteria, the reasons

The distressful life of FtsZ-deprived bacteria

Failure to assemble a division septum occurs in Escherichia coli cells when their supply of FtsZ is blocked. FtsZ, ancestor of eukaryotic Tubulin, is the main component of the divisome, the molecular machinery that drives septation in

Studying potential endocrine disrupting chemicals: comparison of yeast and human cell-based in vitro assays

The production of chemicals for agricultural and industrial use, cosmetics or food additives is steadily increasing. To protect the environment and human health against the potential risks arising from these man-made chemicals, the authorities introduced several programs

Limiting environment speeds up the opening of serotinous cones and decreases aerial cone banks

Serotiny, the maintenance of closed cones after maturation (Fig. 1), is a key adaptive trait of plants in fire-prone environments. However, in moderately serotinous species, cones may open in the absence of fire under hot and dry

Screening sunscreens: protecting the biomechanical barrier of skin from ultraviolet radiation damage

The uppermost layer of human skin, known as the stratum corneum (SC), is the most important physical barrier between the human body and the environment and plays a surprisingly acute role in the mechanical function of full

A sticky, flexible and strong material for better dentistry

Restorations of endodontically treated teeth represent a big part of modern restorative treatment. A post and core should be fabricated to provide retention for the coronal restoration- most often an indirectly made crown. Traditionally metal cast post